PHPID

Public Health Preparedness for Infectious Disease

Molecular Dissection of Respiratory Syncytial Virus Infection

A study published this week in PLOS Medicine reveals profound systemic dysregulation of the immune response induced by RSV infection in young children and suggest that molecular markers might be able to predict disease severity. RSV is responsible for a substantial fraction of serious respiratory infections and deaths among young children worldwide and a top candidate for vaccine development. A team of researchers led by Asuncion Mejias and Octavio Ramilo, both from The Research Institute at Nationwide Children's Hospital, and The Ohio State University College of Medicine, examined the global gene expression patterns in blood samples from four different cohorts of children who were hospitalized with lower respiratory tract infections. Read the entire article here:  Medical Xpress